The TNFSF14 Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to CD258, LIGHT, LTg, and TNFSF14. This antibody recognizes Human antigen. The TNFSF14 Antibody (Center) has been validated for the following applications: ELISA, and Western Blot.
Description
The protein encoded by this gene is a member of the tumor
necrosis factor (TNF) ligand family. This protein is a ligand for
TNFRSF14, which is a member of the tumor necrosis factor receptor
superfamily, and which is also known as a herpesvirus entry
mediator (HVEM). This protein may function as a costimulatory
factor for the activation of lymphoid cells and as a deterrent to
infection by herpesvirus. This protein has been shown to stimulate
the proliferation of T cells, and trigger apoptosis of various
tumor cells. This protein is also reported to prevent tumor
necrosis factor alpha mediated apoptosis in primary hepatocyte. Two
alternatively spliced transcript variant encoding distinct isoforms
have been reported